PlateletWeb - Systems Biology Workbench

Legend

Proteins

Icons describing the level of detection for each protein

	Proteome proteins found on the level of the platelet proteome
	SAGE proteins found on the level of the platelet transcriptome
	Both proteins found on the level of the platelet proteome as well as on the level of the transcriptome
	None proteins which have not been detected in the platelet

Type of Experiment

Icons describing the type of experiment which detects the interactions and phosphorylations of the proteins

	in vivo Experiment
	in vitro Experiment
	Y2H Experiment

Protein Phosphorylations

Icons describing the type of phosphorylations of each protein

	Experimental Platelet Phosphorylation S/T denotes platelet proteins phosphorylated on serine or/and threonine residues. The phosphosites are detected in platelets
	Experimental Platelet Phosphorylation Y denotes platelet proteins phosphorylated on a tyrosine residue. The phosphosites are detected in platelets
	Experimental Platelet Phosphorylation S/T/Y denotes proteins phosphorylated on serine or/and threonine as well as tyrosine residues. The phosphosites are detected in platelets
	Experimental Human Phosphorylation S/T denotes proteins phosphorylated on serine or/and threonine residues. The phosphosites are detected in human cells
	Experimental Human Phosphorylation Y denotes proteins phosphorylated on a tyrosine residue. The phosphosites are detected in human cells
	Experimental Human Phosphorylation S/T/Y denotes proteins phosphorylated on serine or/and threonine as well as tyrosine residues. The phosphosites are detected in human cells

Kinase Type

Icons describing the type of kinase

	S/T Kinase denotes kinases that phosphorylate targets on serine or/and threonine residues
	Y Kinase denotes kinases that phosphorylate targets on tyrosine residues
	S/T/Y Kinase denotes kinases that phosphorylate targets on serine or/and threonine as well as tyrosine residues

Phosphatases

Icon describing the Phosphatasae

Phosphatase denotes manually curated protein phosphotases

Sources of Information

Icons describing the source of information about interactions and phosphorylations of the proteins

	HPRD denotes HPRD (Human Protein Reference Database) as the source of phosphorylation information
	PhosphoSite denotes PhosphoSite as the source of phosphorylation information
	NetworKIN denotes NetworKIN as the source of kinase predictions for experimentally derived platelet phosphorylations

Interaction Type

Icons describing the Interaction type of the proteins

	Protein-protein interaction denotes interactions between proteins based on the NCBI dataset (Entrez gene)
	Phosphorylation denotes phosphorylation reactions (kinases) derived from annotations in the HPRD and PhosphoSite databases
	Kinase prediction denotes phosphorylation reactions for kinases predicted by NetworKIN for experimentally derived platelet phosphorylations
	Dephosphorylation denotes dephosphorylation reactions (phosphatases) derived from annotations in the HPRD database