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Description for Protein NR1H4

nuclear receptor subfamily 1, group H, member 4
16 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • ZnF_C4: c4 zinc finger in nuclear hormone receptors
  • HOLI: Ligand binding domain of hormone receptors
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08537
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Farnesoid X activated receptor; FXR; Retinoid X receptor interacting protein 14; RIP14; Bile acid receptor; BAR; Farnesol receptor HRR 1; Nuclear receptor subfamily 1, group H, member 4
    Approved Symbol:
    NR1H4
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid(db);
  • Chenodeoxycholic acid(db);
  • Fexaramine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04827 Entrez Gene ID: 9971 OMIM ID: 603826 Swissprot Accession: Q96RI1; B6ZGS9;