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Description for Protein SRGAP3

SLIT-ROBO Rho GTPase activating protein 3
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(phosphoproteome: 1; undefined: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • FCH: Fes/CIP4 homology domain
  • CC: Coiled Coil
  • RHOGAP: GTPase-activator protein for Rho-like GTPases
  • SH3: Src homology 3 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07526
    KEGG - Pathway(s):
    hsa04360
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    MEGAP; ARHGAP14; KIAA0411; SLIT ROBO Rho GTPase activating protein 3; WAVE associated Rac GTPase activating protein; SLIT ROBO GAP 3; Rho GTPase activating protein 14; Mental disorder associated GAP; WRP; SLIT-ROBO Rho GTPase activating protein 3 isoform b; SLIT-ROBO Rho GTPase activating protein 3 isoform a
    Approved Symbol:
    SRGAP3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; Platelet phosphorylation sites: 1
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12108 Entrez Gene ID: 9901 OMIM ID: 606525 Swissprot Accession: O43295;