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Description for Protein CDC5L

CDC5 cell division cycle 5-like (S. pombe)
52 total interacting proteins; 16 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • SANT: SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12860
    KEGG - Pathway(s):
    hsa03040
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CDC5 related protein; PCDC5RP
    Approved Symbol:
    CDC5L
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 25
    Human (de-) phosphorylation sites: 25; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04184 Entrez Gene ID: 988 OMIM ID: 602868 Swissprot Accession: Q99459;