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Description for Protein SLK

STE20-like kinase
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 3)
Summary:
(PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K08836
    KEGG - Pathway(s):
    hsa04114
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    STE20-like kinase; STK2; Se20-9; KIAA0204; CTCL tumor antigen se20-9; Ste20-related serine/threonine kinase; Serine/threonine kinase 2
    Approved Symbol:
    SLK
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 54
    Human (de-) phosphorylation sites: 54; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE(db);
  • [4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11585 Entrez Gene ID: 9748 OMIM ID: - Swissprot Accession: Q9H2G2;