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Description for Protein ARHGAP32

Rho GTPase activating protein 32
30 total interacting proteins; 19 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RHOGAP: GTPase-activator protein for Rho-like GTPases

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    MGC1892; p250GAP; GAB associated CDC42; Rac GTPase activating protein; Rho GTPase activating protein; GTPase interacting with TRKA; GRIT; p200RhoGAP; KIAA0712; GC-GAP
    Approved Symbol:
    ARHGAP32
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 46
    Human (de-) phosphorylation sites: 46; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 12257 Entrez Gene ID: 9743 OMIM ID: 608541 Swissprot Accession: Q86T64A7KAX9