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Description for Protein CD79A

CD79a molecule, immunoglobulin-associated alpha
22 total interacting proteins; 11 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
  • ITAM: Immunoreceptor tyrosine-based activation motif
  • IGC2: Immunoglobulin C-2 Type
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06506
    KEGG - Pathway(s):
    hsa04662; hsa05340
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    B cell antigen receptor complex associated protein alpha chain; B lymphocyte specific MB1 protein; MB 1 membrane glycoprotein; Surface IgM associated protein; Membrane bound immunoglobulin associated protein; IGA; MB1; Immunoglobulin associated alpha; CD79A antigen isoform 2 precursor; CD79A antigen isoform 1 precursor
    Approved Symbol:
    CD79A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 8
    Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 2
  • Isoform 1 : 2
    • Additional Identifiers:

    HPRD: 00203 Entrez Gene ID: 973 OMIM ID: 112205 Swissprot Accession: P11912; A0N775;