Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein IKBKE

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
34 total interacting proteins; 23 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.7.11.10
KEGG - Orthology:
K07211
KEGG - Pathway(s):
hsa04620; hsa04622; hsa04623
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Inhibitor of kappa light polypeptide gene enhancer in B cells; Kinase epsilon; IKK related kinase epsilon; Inducible IkappaB kinase; IKKI; IKKi; KIAA0151
Approved Symbol:
IKBKE
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 5
Human phosphorylation targets: 5; Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05442 Entrez Gene ID: 9641 OMIM ID: 605048 Swissprot Accession: Q14164;