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Description for Protein CREB5

cAMP responsive element binding protein 5
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ZNFC2: zinc finger
  • BRLZ: basic region leucin zipper
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09047
    KEGG - Pathway(s):
    hsa04962; hsa05016; hsa05215
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CRE BPA; H_GS165L15.1; cAMP response element-binding protein CRE-BPa; cAMP responsive element binding protein 5 isoform alpha; cAMP responsive element binding protein 5 isoform delta; cAMP responsive element binding protein 5 isoform beta; cAMP responsive element binding protein 5 isoform gamma
    Approved Symbol:
    CREB5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 12
    Human (de-) phosphorylation sites: 12; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09896 Entrez Gene ID: 9586 OMIM ID: - Swissprot Accession: Q02930; Q59G47; B5BUH3;