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Description for Protein SOX13

SRY (sex determining region Y)-box 13
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • HMG: high mobility group
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09269
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    SRY box 13; Type 1 diabetes autoantigen; SRY related HMG box gene 13; SRY related HMG box gene 12; ICA12; MGC117216; Islet cell antibody 12; Islet cell antigen 12; Type 1 diabetes autoantigen ICA12
    Approved Symbol:
    SOX13
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 18
    Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 2
    • Additional Identifiers:

    HPRD: 09205 Entrez Gene ID: 9580 OMIM ID: 604748 Swissprot Accession: Q9UN79;