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Description for Protein GOSR2

golgi SNAP receptor complex member 2
4 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08496
    KEGG - Pathway(s):
    hsa04130
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Golgi SNARE 27-KD; Membrin; 27 kDa Golgi SNARE protein; GS27; Golgi SNAP receptor complex member 2 isoform B; Golgi SNAP receptor complex member 2 isoform A; Golgi SNAP receptor complex member 2 isoform C
    Approved Symbol:
    GOSR2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 1
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04937 Entrez Gene ID: 9570 OMIM ID: 604027 Swissprot Accession: O14653; Q8N4B8;