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Description for Protein BCAR1

breast cancer anti-estrogen resistance 1
57 total interacting proteins; 33 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SH3: Src homology 3 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05726
    KEGG - Pathway(s):
    hsa04062; hsa04510; hsa04670; hsa04810; hsa05100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Breast cancer antiestrogen resistance 1; p130CAS; CRKAS; CAS
    Approved Symbol:
    BCAR1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 29
    Human (de-) phosphorylation sites: 29; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04248 Entrez Gene ID: 9564 OMIM ID: 602941 Swissprot Accession: B3KWE2; P56945; B4DIW5;