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Description for Protein ATP6V1G1

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 2)
Summary:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.3.14
    KEGG - Orthology:
    K02152
    KEGG - Pathway(s):
    hsa00190; hsa01100; hsa04966; hsa05110; hsa05120
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    ATP6G1; ATPase, H+ transporting, lysosomal, 13KD, V1 subunit G, isoform 1; Vacuolar ATP synthase subunit G 1; V ATPase G subunit 1; Vacuolar proton pump G subunit 1; V ATPase 13 kDa subunit 1; Vacuolar ATP synthase subunit M16; ATP6G; ATP6J
    Approved Symbol:
    ATP6V1G1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06294 Entrez Gene ID: 9550 OMIM ID: 607296 Swissprot Accession: O75348; Q6IB33;