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Description for Protein GAL3ST1

galactose-3-O-sulfotransferase 1
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.8.2.11
    KEGG - Orthology:
    K01019
    KEGG - Pathway(s):
    hsa00600; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Cerebroside (3`-phosphoadenylylsulfate:galactosylceramide 3`) sulfotransferase; CST; GalCer sulfotransferase; 3 Prime phosphoadenylyl sulfate; Galactosylcermide 3 prime sulfotransferase; 3 Prime phosphoadenylylsulfate:galactosylceramide 3 prime sulfotransferase; 3 Prime phosphoadenosine 5 prime phosphosulfate:GalCer sulfotransferase; Galactosylceramide sulfotransferase
    Approved Symbol:
    GAL3ST1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 03806 Entrez Gene ID: 9514 OMIM ID: 602300 Swissprot Accession: Q99999;