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Description for Protein CD33

CD33 molecule
4 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • IG: Immunoglobulin
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06473
    KEGG - Pathway(s):
    hsa04640
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CD33 antigen (gp67) isoform 2 precursor; CD33 antigen (gp67) isoform 1 precursor; Myeloid differentiation antigen CD33; Sialic acid binding immunoglobulin like lectin 3; SIGLEC3; p67; gp67; Siglec-3
    Approved Symbol:
    CD33
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Gemtuzumab ozogamicin(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 01165 Entrez Gene ID: 945 OMIM ID: 159590 Swissprot Accession: P20138; Q546G0; C9JEN7;