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Description for Protein PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A
18 total interacting proteins; 13 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/2)
(phosphoproteome: 1; platelet: 2; undefined: 1)
Summary:
PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12328
KEGG - Pathway(s):
hsa04270
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
17-kDa PKC-potentiated inhibitory protein of PP1; CPI-17; Protein kinase C-potentaited inhibitor of protein phosphatase 1, 17-KD
Approved Symbol:
PPP1R14A
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 7
Human (de-) phosphorylation sites: 7; Platelet phosphorylation sites: 4
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16291 Entrez Gene ID: 94274 OMIM ID: 608153 Swissprot Accession: Q96A00;