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Description for Protein KCNK6

potassium channel, subfamily K, member 6
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04917
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Potassium channel weakly inward retifying with twin P domains; TWIK2; TWIK originated similarity sequence; TOSS; TWIK originated sodium similarity sequence potassium channel, subfamily K, member 6; Inward rectifying potassium channel protein TWIK2
    Approved Symbol:
    KCNK6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Ibutilide(db);
  • Quinidine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 6
    • Additional Identifiers:

    HPRD: 06803 Entrez Gene ID: 9424 OMIM ID: 603939 Swissprot Accession: Q9Y257; B2RDS2;