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Description for Protein SLC22A6

solute carrier family 22 (organic anion transporter), member 6
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08203
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    OAT1; PAHT; ROAT1; HOAT1; MGC45260; PAH transporter; Organic anion transporter 1; Para aminohippurate transporter; Renal organic anion transporter 1; Solute carrier family 22 organic anion transporter, member 6; Solute carrier family 22 member 6 isoform b; Solute carrier family 22 member 6 isoform e; Solute carrier family 22 member 6 isoform d; Solute carrier family 22 member 6 isoform c; Solute carrier family 22 member 6 isoform a
    Approved Symbol:
    SLC22A6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Probenecid(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
    12125_5(10)
  • Isoform 4 : 9
  • Isoform 3 : 9
    12125_2(10)
  • Isoform 1 : 9
    • Additional Identifiers:

    HPRD: 12125 Entrez Gene ID: 9356 OMIM ID: 607582 Swissprot Accession: Q4U2R8; B3KP57;