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Description for Protein TAOK2

TAO kinase 2
6 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
TAOK2 is a serine/threonine kinase that has a role in cell signaling, microtubule organization and stability, and in apoptosis (Moore et al., 2000 [PubMed 10660600]; Zihni et al., 2007 [PubMed 17158878]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K04429
    KEGG - Pathway(s):
    hsa04010
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    TAO1; KIAA0881; PSK; PSK1; TAO2; MAP3K17; Prostate derived STE20 like kinase PSK; Thousand and one amino acid protein kinase; Serine/threonine protein kinase TAO2; EC 2.7.1.37; Prostate derived STE20 like kinase 1; hKFC C; TAO kinase 2 isoform 2; TAO kinase 2 isoform 1
    Approved Symbol:
    TAOK2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 19
    Human (de-) phosphorylation sites: 19; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Phosphonoserine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 4
    • Additional Identifiers:

    HPRD: 18147 Entrez Gene ID: 9344 OMIM ID: 613199 Swissprot Accession: A7MCZ2; Q9UL54; A0PJ48;