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Description for Protein MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Hematopoietic specific transmembrane 4 protein; Hematopoietic cell 4 transmembrane protein; CD20 antigen-like protein; HTM4; CD20L; IgE receptor beta chain; IgE receptor beta subunit; Membrane-spanning 4-domains, subfamily A, member 3 isoform c; Membrane-spanning 4-domains, subfamily A, member 3 isoform b
    Approved Symbol:
    MS4A3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 2
  • Isoform 2 : 2
  • Isoform 1 : 4
    • Additional Identifiers:

    HPRD: 09403 Entrez Gene ID: 932 OMIM ID: 606498 Swissprot Accession: Q96HJ5; A8MTP8;