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Description for Protein RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5
32 total interacting proteins; 15 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K04445
    KEGG - Pathway(s):
    hsa04010; hsa04722; hsa05219
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Mitogen and stress activated protein kinase 1; MSK1; 90 kDa ribosomal protein S6 kinase 5; RSK-like protein kinase; RLSK; RLPK; MGC1911; MSPK1; Ribosomal protein S6 kinase, 90kDa, polypeptide 5; EC 2.7.1.37; Ribosomal protein S6 kinase, 90kDa, polypeptide 5 isoform b; Ribosomal protein S6 kinase, 90kDa, polypeptide 5 isoform a
    Approved Symbol:
    RPS6KA5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 12
    Human (de-) phosphorylation sites: 12; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 20
    Human phosphorylation targets: 20; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Beta-Mercaptoethanol(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06789 Entrez Gene ID: 9252 OMIM ID: 603607 Swissprot Accession: O75582; Q9UG98;