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Description for Protein SLC33A1

solute carrier family 33 (acetyl-CoA transporter), member 1
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.3.1.-
    KEGG - Orthology:
    K03372
    KEGG - Pathway(s):
    hsa00604; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Acatn; Solute carrier family 33 (acetyl-CoA transporter), member 1
    Approved Symbol:
    SLC33A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
    04734_1(11)
    Additional Identifiers:

    HPRD: 04734 Entrez Gene ID: 9197 OMIM ID: 603690 Swissprot Accession: O00400;