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Description for Protein ZW10

ZW10, kinetochore associated, homolog (Drosophila)
8 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 2; undefined: 1)
Summary:
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K11578
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    HZW10; KNTC1AP; MGC149821; Centromere/kinetochore protein; Centromere/kinetochore protein zw10; Zeste white 10 homolog; ZW10 homolog, centromere/kinetochore protein
    Approved Symbol:
    ZW10
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04902 Entrez Gene ID: 9183 OMIM ID: 603954 Swissprot Accession: O43264;