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Description for Protein HGS

hepatocyte growth factor-regulated tyrosine kinase substrate
100 total interacting proteins; 55 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(microparticles: 1; platelet: 2)
Summary:
(PubMed Links)
Domains and Motifs:
  • VHS: Domain present in VPS-27, Hrs and STAM
  • FYVE: Protein present in Fab1, YOTB, Vac1, and EEA1
  • UIM: Ubiquitin-interacting motif.
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12182
    KEGG - Pathway(s):
    hsa04144
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Hepatocyte growth factor regulated tyrosine kinase substrate; Human growth factor regulated tyrosine kinase substrate; HGF regulated tyrosine kinase substrate
    Approved Symbol:
    HGS
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 18
    Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Citric Acid(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05085 Entrez Gene ID: 9146 OMIM ID: 604375 Swissprot Accession: O14964;