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Description for Protein CCNB2

cyclin B2
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K05868
KEGG - Pathway(s):
hsa04110; hsa04114; hsa04115; hsa04914
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
G2/mitotic specific cyclin B2; HsT17299
Approved Symbol:
CCNB2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 8
Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 04131 Entrez Gene ID: 9133 OMIM ID: 602755 Swissprot Accession: O95067