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Description for Protein PIGQ

phosphatidylinositol glycan anchor biosynthesis, class Q
5 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03860
    KEGG - Pathway(s):
    hsa00563; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Phosphatidylinositol glycan, class Q isoform 2; Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q; Phosphatidylinositol-glycan biosynthesis, class Q protein; PIG-Q; N-acetylglucosamyl transferase component GPI1; EC 2.4.1.198; Phosphatidylinositol glycan, class Q isoform 1
    Approved Symbol:
    PIGQ
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 5
  • Isoform 1 : 4
    • Additional Identifiers:

    HPRD: 09307 Entrez Gene ID: 9091 OMIM ID: 605754 Swissprot Accession: Q9BRB3;