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Description for Protein CCT6A

chaperonin containing TCP1, subunit 6A (zeta 1)
15 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 6/1)
(membrane: 1; microparticles: 1; platelet: 3; secretome: 2; undefined: 1)
Summary:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K09498
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Chaperonin containing TCP1 subunit 6A zeta 1; Chaperonin containing T-complex subunit 6; T complex protein, zeta 1 subunit; TCP 1 zeta; CCT zeta; CCT zeta 1; Tcp20; HTR3; T complex homolog TCP20; CCT6; Histidine transport regulator 3; Amino acid transport defect complementing; Cctz; TCPZ; TTCP20; Chaperonin containing TCP1, subunit 6A isoform b; Chaperonin containing TCP1, subunit 6A isoform a; MoDP 2; MGC126214; MGC126215; Acute morphine dependence related protein 2
Approved Symbol:
CCT6A
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00089 Entrez Gene ID: 908 OMIM ID: 104613 Swissprot Accession: A6NCD2; P40227;