Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein LRSAM1

leucine rich repeat and sterile alpha motif containing 1
28 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 4)
Summary:
LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al., 2003 [PubMed 14635195]; Amit et al., 2004 [PubMed 15256501]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • LRR: Leucine-rich repeats, outliers
  • NLS: Nuclear localization signal
  • CC: Coiled Coil
  • LZ: Leucine Zipper
  • SAM: Sterile alpha motif.
  • RING: Ring finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.3.2.19
    KEGG - Orthology:
    K10641
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    TAL; RIFLE; Tsg101-associated ligase; UNQ6496/PRO21356; FLJ31641; LOC90678; EC 6.3.2
    Approved Symbol:
    LRSAM1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 14325 Entrez Gene ID: 90678 OMIM ID: 610933 Swissprot Accession: Q6UWE0;