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Description for Protein STARD13

StAR-related lipid transfer (START) domain containing 13
14 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein that contains a sterile alpha motif domain in the N-terminus, an ATP/GTP-binding motif, a GTPase-activating protein domain, and a STAR-related lipid transfer domain in the C-terminus. The gene is located in a region of chromosome 13 that has loss of heterozygosity in hepatic cancer. At least three alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RHOGAP: GTPase-activator protein for Rho-like GTPases
  • START: in StAR and phosphatidylcholine transfer protein

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    START domain containing 13 isoform beta; START domain containing 13 isoform gamma; GT650; 46H23.2; StARD13; Deleted in liver cancer 2; StAR related lipid transfer protein 13; START domain containing protein 13; Rho GTPase activating protein on chromosome 13q12; DLC2; START domain containing 13 isoform alpha
    Approved Symbol:
    STARD13
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 11607 Entrez Gene ID: 90627 OMIM ID: 609866 Swissprot Accession: Q9Y3M8B2R789