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Description for Protein FGD3

FYVE, RhoGEF and PH domain containing 3
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(phosphoproteome: 1; platelet: 3; undefined: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • RHOGEF: Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
  • PH: Pleckstrin homology domain.
  • FYVE: Protein present in Fab1, YOTB, Vac1, and EEA1
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05722
    KEGG - Pathway(s):
    hsa04810
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    ZFYVE5; FLJ00004; FGD3 protein; Faciogenital dysplasia 3
    Approved Symbol:
    FGD3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; Platelet phosphorylation sites: 1
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10957 Entrez Gene ID: 89846 OMIM ID: - Swissprot Accession: Q5JSP0;