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Description for Protein AP1M1

adaptor-related protein complex 1, mu 1 subunit
26 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 5/1)
(membrane: 2; microparticles: 1; platelet: 3; secretome: 1; undefined: 1)
Summary:
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12393
KEGG - Pathway(s):
hsa04142
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Clathrin adaptor protein AP47; HA1 47 kDa subunit; Golgi adaptor AP-1 47 kDa protein; AP mu chain family member mu1A; Mu-adaptin 1; CLTNM; CLAPM2; MU-1A
Approved Symbol:
AP1M1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04639 Entrez Gene ID: 8907 OMIM ID: 603535 Swissprot Accession: Q9BXS5; Q4TTY5; Q59EK3;