Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ACTN3

actinin, alpha 3
6 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CH: Calponin homology domain
  • CC: Coiled Coil
  • SPECTRIN: Spectrin repeat
  • EF: EF-hand, calcium binding motif
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05699
    KEGG - Pathway(s):
    hsa04510; hsa04520; hsa04530; hsa04670; hsa04810; hsa05322; hsa05412
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Alpha actinin 3; F actin cross linking protein
    Approved Symbol:
    ACTN3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Actinin, alpha-3 polymorphism(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02148 Entrez Gene ID: 89 OMIM ID: 102574 Swissprot Accession: Q08043;