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Description for Protein PRPF4B

PRP4 pre-mRNA processing factor 4 homolog B (yeast)
10 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K08827
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    RP5-1013A10.2; PRP4; dJ1013A10.1; OTTHUMP00000039176; dJ1013A10.1 (PRP4 protein kinase homolog); Protein-serine/threonine kinase; Serine/threonine-protein kinase PRP4K; EC 2.7.1.37; PR4H; PRP4H; PRP4K; PRP4 kinase; KIAA0536; Serine/threonine-protein kinase PRP4 homolog
    Approved Symbol:
    PRPF4B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 66
    Human (de-) phosphorylation sites: 66; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09087 Entrez Gene ID: 8899 OMIM ID: 602338 Swissprot Accession: Q13523;