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Description for Protein AKAP4

A kinase (PRKA) anchor protein 4
7 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
A kinase anchor protein, 82-KD; AKAP82; A kinase (PRKA) anchor protein 4; Testis specific gene HI; HI; FSC1; p82; A-kinase anchor protein 4 isoform 2; Protein kinase A anchoring protein 4; hAKAP82; A kinase anchor protein 4 isoform 1; RP13-377G1__B.1
Approved Symbol:
AKAP4
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 59
Human (de-) phosphorylation sites: 59; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 02173 Entrez Gene ID: 8852 OMIM ID: 300185 Swissprot Accession: Q5JQC9