Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein CFLAR

CASP8 and FADD-like apoptosis regulator
37 total interacting proteins; 17 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • DED: Death effector domain
  • CASc: Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04724
    KEGG - Pathway(s):
    hsa04210; hsa05142
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FLICE inhibitory protein; CASP8 and FADD like apoptosis regulator; Cellular FLICE like inhibitory protein; Caspase-8 related protein; Caspase like apoptosis regulatory protein; Inhibitor of FLICE; FADD like antiapoptotic molecule 1; Flame 1; Usurpin; Casper; CLARP; MACH related inducer of toxicity; MRIT; I-FLICE; CASH
    Approved Symbol:
    CFLAR
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04671 Entrez Gene ID: 8837 OMIM ID: 603599 Swissprot Accession: O15519; Q53TS6;