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Description for Protein RIPK1

receptor (TNFRSF)-interacting serine-threonine kinase 1
44 total interacting proteins; 13 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 2)
Summary:
(PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
  • CC: Coiled Coil
  • DEATH: DEATH domain, found in proteins involved in cell death (apoptosis).
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K02861
    KEGG - Pathway(s):
    hsa04210; hsa04620; hsa04622; hsa04623
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    RIP; FLJ39204; RIP1; OTTHUMP00000039163; Receptor interacting protein; EC 2.7.11.1; Serine/threonine-protein kinase RIP; Cell death protein RIP
    Approved Symbol:
    RIPK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04583 Entrez Gene ID: 8737 OMIM ID: 603453 Swissprot Accession: Q13546;