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Description for Protein TNK1

tyrosine kinase, non-receptor, 1
3 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
TNK1 is a nonreceptor tyrosine kinase. These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • Tyr_Kinase: tyrosine kinase domain
  • SH3: Src homology 3 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.10.2
    KEGG - Orthology:
    K08885
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Tyrosine kinase, non-receptor, 1; CD38 negative kinase
    Approved Symbol:
    TNK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 19
    Human (de-) phosphorylation sites: 19; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09730 Entrez Gene ID: 8711 OMIM ID: 608076 Swissprot Accession: Q13470;