Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein STX16

syntaxin 16
6 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 13)
Summary:
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • t_SNARE: Helical region found in SNAREs
  • TM: Transmembrane domain
  • SynN: Syntaxin N-terminal domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08489
    KEGG - Pathway(s):
    hsa04130
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Syn16; hsyn16; Syntaxin 16 isoform a; Syntaxin 16 isoform b
    Approved Symbol:
    STX16
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Pseudohypoparathyroidism, type IB(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 5 : 1
  • Isoform 4 : 1
  • Isoform 3 : 0
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 04718 Entrez Gene ID: 8675 OMIM ID: 603666 Swissprot Accession: O14662; Q6GMS8; Q96JR6;