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Description for Protein CDK10

cyclin-dependent kinase 10
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • NLS: Nuclear localization signal
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.22
    KEGG - Orthology:
    K02449
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    PISSLRE; CDC2 related protein kinase; Cell division protein kinase 10; Cyclin dependent kinase related protein; Cyclin dependent kinase 10; Cyclin-dependent kinase 10 isoform 1; Serine/threonine protein kinase PISSLRE; EC 2.7.1.37; Cyclin-dependent kinase 10 isoform b; Cyclin-dependent kinase 10 isoform c
    Approved Symbol:
    CDK10
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04588 Entrez Gene ID: 8558 OMIM ID: 603464 Swissprot Accession: Q15131; B7Z537;