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Description for Protein BHLHE40

basic helix-loop-helix family, member e40
10 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ORANGE: Orange domain
  • HLH: helix loop helix domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03729
    KEGG - Pathway(s):
    hsa04710
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    DEC1; Class B basic helix loop helix protein 2; Differentially expressed in chondrocytes protein 1; Enhancer of split and hairy related protein 2; SHARP 2; Split and hairy related protein 2; STRA13; Stimulated with retinoic acid 13; Stra14
    Approved Symbol:
    BHLHE40
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16050 Entrez Gene ID: 8553 OMIM ID: 604256 Swissprot Accession: O14503; Q6IB83;