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Description for Protein MYLK2

myosin light chain kinase 2
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 2; undefined: 1)
Summary:
This gene encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.18
    KEGG - Orthology:
    K00907
    KEGG - Pathway(s):
    hsa04020; hsa04270; hsa04510; hsa04810
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Myosin light polypeptide kinase, skeletal/cardiac; MLCK, skeletal/cardiac; MLCK2
    Approved Symbol:
    MYLK2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Cardiomyopathy, hypertrophic, midventricular, digenic(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05953 Entrez Gene ID: 85366 OMIM ID: 606566 Swissprot Accession: Q9H1R3;