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Description for Protein CAMK1

calcium/calmodulin-dependent protein kinase I
10 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(microparticles: 1; platelet: 4; undefined: 1)
Summary:
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.17
    KEGG - Orthology:
    K08794
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Calcium/calmodulin dependent protein kinase 1
    Approved Symbol:
    CAMK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 11
    Human phosphorylation targets: 11; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05412 Entrez Gene ID: 8536 OMIM ID: 604998 Swissprot Accession: Q14012; B0YIY3;