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Description for Protein DDO

D-aspartate oxidase
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(secretome: 1)
Summary:
The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.4.3.1
    KEGG - Orthology:
    K00272
    KEGG - Pathway(s):
    hsa00250; hsa04146
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Aspartic oxidase; OTTHUMP00000017000; D-aspartate oxidase isoform a; D-aspartate oxidase isoform b; Hypothatical protein FLJ45203; DASOX; D ASPOX; EC 1.4.3.1
    Approved Symbol:
    DDO
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00498 Entrez Gene ID: 8528 OMIM ID: 124450 Swissprot Accession: Q99489;