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Description for Protein KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2
7 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 12)
Summary:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K04883
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
KCNA2B; KCNA2 beta; KV-Beta-2; AKR6A5; HKvbeta2; KV-BETA-2; HKvbeta2.1; HKvbeta2.2; K+ channel beta 2 subunit; Potassium channel shaker chain beta 2; KCNK2
Approved Symbol:
KCNAB2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 11
Human (de-) phosphorylation sites: 11; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03090 Entrez Gene ID: 8514 OMIM ID: 601142 Swissprot Accession: Q13303;