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Description for Protein PCGF1

polycomb group ring finger 1
9 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RING: Ring finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K11487
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    MGC10882; Nervous System Polycomb 1; Hypothetical protein MGC10882; Polycomb group ring finger 1; RNF68; RNF3A-2; FLJ43754; 2010002K04Rik; RING finger protein 68
    Approved Symbol:
    PCGF1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11404 Entrez Gene ID: 84759 OMIM ID: 610231 Swissprot Accession: Q9BSM1;