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Description for Protein GPT2

glutamic pyruvate transaminase (alanine aminotransferase) 2
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.6.1.2
KEGG - Orthology:
K00814
KEGG - Pathway(s):
hsa00250; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Alanine aminotransferase 2; ALT2; Glutamic Pyruvate Transaminase 2
Approved Symbol:
GPT2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Alanine(db);
  • L-Glutamic Acid(db);
  • Phenelzine(db);
  • Pyridoxal Phosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06307 Entrez Gene ID: 84706 OMIM ID: 138210 Swissprot Accession: Q8TD30;