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Description for Protein TAF3

TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • PHD: PHD zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    MGC25063; RNA polymerase II transcription factor TAFII140; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140 kD; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa (TAF3)(TAF140,TAFII140); Transcription initiation factor TFIID subunit 3; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; 140 kDa TATA box-binding protein-associated factor; TAFII140; TAF140
    Approved Symbol:
    TAF3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 27
    Human (de-) phosphorylation sites: 27; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 19377 Entrez Gene ID: 83860 OMIM ID: 606576 Swissprot Accession: Q5VWG9;