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Description for Protein BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
22 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.4.19.12
KEGG - Orthology:
K08588
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
HUCEP-13; KIAA0272; Hucep-6; BRCA1 associated protein-1; Cerebral protein-13; Cerebral protein-6; Ubiquitin carboxy-terminal hydrolase
Approved Symbol:
BAP1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 19
Human (de-) phosphorylation sites: 19; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04366 Entrez Gene ID: 8314 OMIM ID: 603089 Swissprot Accession: Q92560;