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Description for Protein CAPZA1

capping protein (actin filament) muscle Z-line, alpha 1
8 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 11/1)
(alpha granules: 1; membrane: 2; microparticles: 1; platelet: 6; secretome: 2)
Summary:
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K10364
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
CAZ1; CAPPA1; CAPZ; Cap protein, actin, alpha 1 subunit; Capping protein, actin filament, muscle Z-line, alpha 1; F-actin capping protein, alpha 1 subunit; CAPZ alpha 1; EcapZ
Approved Symbol:
CAPZA1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03347 Entrez Gene ID: 829 OMIM ID: 601580 Swissprot Accession: P52907;