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Description for Protein KDM5D

lysine (K)-specific demethylase 5D
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PHD: PHD zinc finger
  • CC: Coiled Coil
  • JMJC: A domain family that is part of the cupin metalloenzyme superfamily.
  • BRIGHT: BRIGHT, ARID (A/T-rich interaction domain) domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.14.11.-
    KEGG - Orthology:
    K11446
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Histocompatibility Y antigen; HY; HYA; Selected cDNA on Y; Jumonji, AT rich interactive domain 1D (RBP2-like); Smcy homolog, Y chromosome; Smcy homolog, Y-linked; H-Y; KIAA0234
    Approved Symbol:
    KDM5D
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Vitamin C(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02464 Entrez Gene ID: 8284 OMIM ID: 426000 Swissprot Accession: B7ZLX1; Q9BY66;